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Yeast Display-Based single Domain
Antibody Discovery Platform
Enabling precise selection control in FACS screening.
Yeast Display-Based Single Domain
Antibody Discovery Platform
Revolutionize Your Single Domain Antibody Discovery with Our High-Throughput Yeast Surface Display Screening Service.
Phage Display-Based Single Domain
Antibody Discovery Platform
Unlock the Full Potential of Single Domain Antibody with Our State-of-the-Art VHH discovery platform.

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技術(shù)服務(wù)

Your partner for camelid-derived mAbs and single domain antibodies discovery and development.

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抗體成藥性評(píng)估

抗體成藥性評(píng)估抗體成藥性由蛋白本身的序列與內(nèi)在結(jié)構(gòu)決定，同時(shí)會(huì)因具體靶點(diǎn)的差異而有所不同。成藥性評(píng)估一般包括抗體的理化與生化特性?xún)刹糠帧＠砘匦缘脑u(píng)估主要關(guān)注膠體穩(wěn)定性、構(gòu)象穩(wěn)定性以及環(huán)境因素的影響。常用方法如AC-SINS、CSI-BLI、CIC、HIC、SGAC-SINS和S…
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穩(wěn)轉(zhuǎn)細(xì)胞株構(gòu)建平臺(tái)

穩(wěn)轉(zhuǎn)細(xì)胞株構(gòu)建平臺(tái)穩(wěn)轉(zhuǎn)細(xì)胞株構(gòu)建是將外源基因?qū)胨拗骷?xì)胞，隨后通過(guò)抗性基因進(jìn)行篩選，并最終經(jīng)鑒定得到目的基因持續(xù)過(guò)表達(dá)的細(xì)胞株。作為最常見(jiàn)的研究工具之一，穩(wěn)定細(xì)胞系在生物醫(yī)學(xué)、生物制藥和農(nóng)業(yè)領(lǐng)域具有廣泛的應(yīng)用前景。NBbiolab具有大量穩(wěn)定細(xì)胞株開(kāi)發(fā)經(jīng)驗(yàn)，結(jié)…
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抗獨(dú)特型抗體制備服務(wù)

抗獨(dú)特型抗體制備服務(wù)抗獨(dú)特型 (Anti-idiotype) 抗體能夠特異性識(shí)別并結(jié)合待測(cè)抗體位于可變區(qū)的獨(dú)特位 (Idiotype) ，在治療性抗體藥物開(kāi)發(fā)過(guò)程中有著非常廣泛的應(yīng)用。由于抗獨(dú)特型抗體與抗藥抗體（Anti-drug antibody, ADA）之間的相似性，可以作為免疫原性和中和抗體研究…
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修飾類(lèi)型抗體制備服務(wù)

修飾類(lèi)型抗體制備服務(wù)蛋白質(zhì)翻譯后修飾(Protein translational modifications,PTMs)通過(guò)功能基團(tuán)或蛋白質(zhì)的共價(jià)添加、調(diào)節(jié)亞基的蛋白水解切割或整個(gè)蛋白質(zhì)的降解，進(jìn)而改變其化學(xué)性質(zhì)或結(jié)構(gòu)，使得蛋白質(zhì)具有更為復(fù)雜的結(jié)構(gòu)和豐富多樣的功能，最終實(shí)現(xiàn)生物學(xué)功能的精細(xì)調(diào)節(jié)…
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雙特異性抗體生產(chǎn)服務(wù)

雙特異性抗體生產(chǎn)服務(wù)雙特異性抗體 (Bispecific antibody) 是一類(lèi)具有雙功能的人工雜交抗體分子，含有兩種不同的抗原結(jié)合位點(diǎn)，能在靶細(xì)胞和效應(yīng)細(xì)胞之間架起橋梁，達(dá)到定向殺傷靶細(xì)胞的作用。雙特異性抗體由于其獨(dú)特的結(jié)構(gòu)、顯著的臨床效果特別是腫瘤領(lǐng)域的治療效果，已…
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抗體片段生產(chǎn)服務(wù)

抗體片段生產(chǎn)服務(wù)NBbiolab擁有成熟的抗體制備平臺(tái)，可提供多種抗體形式的相關(guān)生產(chǎn)服務(wù)，包括單鏈抗體 (scFv)、抗原結(jié)合片段(Fab)、納米抗體 (VHH)、多價(jià)VHH 和抗體融合蛋白（antibody-fusion proteins）、IgG-scFv、tandem-scFvs等。NBbiolab擁有自主優(yōu)化的HEK293/CHO表達(dá)…
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Rapid VHHs Discovery

The precondition for successful generation of sdAbs against any target using phage display is the construction of high-quality sdAb libraries used for the selection. There are several different forms of sdAb libraries that are classified mainly by the…
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Yeast Surface Display

酵母表面展示技術(shù)平臺(tái) 酵母表面展示（Yeast surface display，YSD）是一種強(qiáng)大的蛋白質(zhì)工程技術(shù),是目前蛋白工程中重要的高通量篩選平臺(tái)。酵母細(xì)胞具有真核細(xì)胞翻譯后修飾機(jī)制，能夠幫助目的蛋白正確折疊，可以用來(lái)展示各種真核蛋白，包括抗體、受體、酶和抗原肽等。阿帕…
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Phage Display Screening

Unleash the power of bacteriophages to quickly screen for antibodies with our well established Phage Display Platform.
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PLATFORM

Based on our long-establishing and advanced platform, our scientists are pleased to offer the best professional sdAb-related services to satisfy each demand from our clients.

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酵母表面展示平臺(tái)

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Single Domain Antibody Discovery & Development

With over 10 years' extensive experience and advanced technology platforms, NBbiolab devotes to providing the most appropriate solutions for novel single domain antibody discovery and development projects. Our scientists are pleased to tailor the best-fit proposal to achieve the project objective.

Our customer service representatives are available 24 hours a day, 7 days a week.

膜蛋白抗體發(fā)現(xiàn)

TCR-Mimic antibody

CAR分子發(fā)現(xiàn)

抗小分子抗體發(fā)現(xiàn)

抗小分子免疫復(fù)合物類(lèi)抗體發(fā)現(xiàn)

駝?lì)惪贵w制備服務(wù)

鯊魚(yú)抗體制備服務(wù)

兔單克隆抗體制備服務(wù)

羊單抗抗體制備服務(wù)

蛋白表達(dá)平臺(tái)

重組抗體表達(dá)平臺(tái)

穩(wěn)定細(xì)胞株構(gòu)建平臺(tái)

噬菌體展示技術(shù)平臺(tái)

酵母展示技術(shù)平臺(tái)

人源化改造

早期成藥性評(píng)價(jià)

抗體親和力成熟

技術(shù)服務(wù)

抗體成藥性評(píng)估

穩(wěn)轉(zhuǎn)細(xì)胞株構(gòu)建平臺(tái)

抗獨(dú)特型抗體制備服務(wù)

修飾類(lèi)型抗體制備服務(wù)

雙特異性抗體生產(chǎn)服務(wù)

抗體片段生產(chǎn)服務(wù)

Rapid VHHs Discovery

Yeast Surface Display

Phage Display Screening

PLATFORM

Single Domain Antibody Discovery & Development

研發(fā)平臺(tái)

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